Coordination & Control: MDCAT Notes and MCQs
Receptors โ biological transducers
Receptors convert stimulus energy (light, heat, pressure, chemicals) into electrical nerve impulses.
- Chemoreceptors โ taste, smell, blood CO2/pH. Mechanoreceptors โ touch, pressure (Pacinian corpuscles), hearing, balance. Thermoreceptors โ heat/cold. Photoreceptors โ rods & cones. Nociceptors โ pain.
Neuron
- Cell body (cyton): nucleus + Nissl's granules (rough ER/ribosomes). Dendrites carry impulses towards the cell body. Axon carries impulses away.
- Myelin sheath โ formed by Schwann cells (PNS) / oligodendrocytes (CNS); gaps = nodes of Ranvier โ saltatory conduction (much faster).
- Types: sensory (afferent), motor (efferent), interneurons / associative (within CNS).
Nerve impulse
- A wave of electrochemical change (action potential) travelling along a neuron.
- Resting membrane potential โ โ70 mV (inside negative) maintained by the Na+/K+ pump (3 Na+ out, 2 K+ in).
- Depolarization: Na+ rushes in (to โ +50 mV); repolarization: K+ moves out. Follows the "all-or-none" law.
- At a synapse, neurotransmitters (acetylcholine, adrenaline/noradrenaline) carry the signal across the cleft.
Reflexes
- Reflex = rapid, automatic, involuntary response. Reflex arc: receptor โ sensory neuron โ interneuron (in spinal cord/brain) โ motor neuron โ effector (muscle/gland).
- Classification: spinal (knee jerk, withdrawal) vs cranial (blinking, pupil reflex); unconditioned/inborn vs conditioned/acquired (Pavlov's dog); monosynaptic (knee jerk) vs polysynaptic.
Brain
| Part | Key functions |
|---|---|
| Cerebrum (largest; 2 hemispheres joined by corpus callosum) | Intelligence, memory, learning, voluntary movement, speech, sensory perception (cortex lobes: frontal, parietal, temporal, occipital) |
| Thalamus | Relay centre for sensory impulses to cerebrum |
| Hypothalamus | Body temperature, hunger, thirst, water balance, controls pituitary |
| Midbrain | Visual and auditory reflexes |
| Pons | Bridge; assists breathing regulation |
| Medulla oblongata | Breathing, heart rate, blood pressure, swallowing, coughing, vomiting |
| Cerebellum | Muscle coordination, posture, balance |
Brain stem = midbrain + pons + medulla oblongata.
PMDC learning outcomes for this unit
- Receptors: 5.1 Recognize receptors as transducers sensitive to various stimuli.
- Neurons: 5.2 Explain the structure of a typical neuron (cell body, dendrites, axon and myelin sheath)
- Neurons: 5.3 Define nerve impulse
- Neurons: 5.4 Classify reflexes
- Neurons: 5.5 Briefly explain the functions of components of a reflex arc
- Brain: 5.6 Discuss the main parts of the brain (e.g. components of brain stem, mid brain, cerebellum, cerebrum)
- Brain: 5.7 Describe the functions of each part.